Station Search:
Current position: >> Publication
Publication

1. Rui Zhan#, Youtian Hu#, Lidong Shao#, Xu-Jie Qin, Fang Kuang, Shouzhen Du, Fang Wu* , and Yegao Chen*. Horisfieldones A and B, Two Aromatic Ring-Contracted Dimeric Diarylpropanes with Human DOPA Decarboxylase Inhibitory Activity from Horsfieldia kingie. Organic Letters. 2019 Apr 30;[Epub ahead of print]

2. Youtian Hu#, Lu Wang#, Xu Han#, Yueyang Zhou, Tonghui Zhang, Li Wang, Ting Hong, Wei Zhang, Xun-Xiang Guo, Jielin Sun, Yingxin Qi, Jing Yu*, Hong Liu*, Fang Wu*.Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine γ-Lyase. Journal of Medicinal Chemistry. 2018 Dec 18;62(3):1677–1683.

3. Li Wang#, Hao Cai#, Youtian Hu, Fan Liu, Shengshuo Huang, Yueyang Zhou, Jing Yu*, Jinyi Xu* and Fang Wu*. A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis. Cell Death & Disease. 2018 Sep 26;9(10):1005.

4. Youtian Hu#Juan FengFang Wu*. The Multiplicity of Polypeptide GalNAc-Transferase: Assays, Inhibitors and Structures. ChemBioChem. 2018 Dec 18;19(24):2503-2521.

5. Zhixue Du#, Jing Yu#, Fucai Li, Liyun Deng, Fang Wu, Xiangyi Huang, Jan Bergstrand, Jerker Widengren, Chaoqing Dong, and Jicun Ren. In Situ Monitoring of p53 Protein and MDM2 Protein Interaction in Single Living Cells Using Single-Molecule Fluorescence Spectroscopy. Anal Chem. 2018 May 15;90(10):6144-6151.

6. 王莉#, 周越洋, 吴方*. 胱硫醚β合酶天然产物抑制剂的高通量筛选. 生物技术. 2017(2):167-173.

7. Feng Liu#, Kai Xu#, Zhijue Xu, Matilde de las Rivas, Congrong Wang, Xing Li, Jishun Lu, Yueyang Zhou, Ignacio Delso, Pedro Merino, Ramon Hurtado-Guerrero*, Yan Zhang* and Fang Wu*. The small molecule luteolin inhibits N-acetyl-α-galactosaminyltransferases and reduces mucin-type O-glycosylation of amyloid precursor protein. Journal of Biological Chemistry. 2017 Dec 29;292(52):21304-21319.

8. Hermeto Gerber#, Fang Wu#, Mitko Dimitrov , Guillermo M. Garcia Osuna , and Patrick C. Fraering. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production. Journal of Biological Chemistry. 2017 Mar 3;292(9):3751-3767.

9. Yinzhong Lu, Jun Wan#, Zhifeng Yang#, Xiling Lei, Qi Niu, Lanxin Jiang, Willemijn M. Passtoors, Aiping Zang, Patrick C. Fraering, and Fang Wu*. Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells. The FASEB Journal. 2017 Apr;31(4):1382-1397.

10. ShuyangXu#, XianminZhu#, Hong Li#, Youtian Hu, JinpingZhou, Di He, Yun Feng, Lina Lu, Guizhen Du, Youjin Hu, Tiancheng Liu, ZhenWang, Guohui Ding, JiayuChen, ShaorongGao, Fang Wu, ZhigangXue, Yixue Li & Guoping Fan. The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat. Scientific Reports. 2016 Jul 5;6:28508.

11. Shengtao Xu, Shanshan Lu, Hong Yao, Hao Cai, Xiaoming Miao, Fang Wu*, Dong-Hua Yang, Xiaoming Wu, Weijia Xie, Hequan Yao, Zhe-sheng Chen, Jinyi Xu. Probing the Anticancer Action of Oridonin with Fluorescent Analogues: Visualizing Subcellular Localization to Mitochondria. J Med. Chem. 2016 May 26;59(10):5022-34.

12. Xiling Lei#, Jing Yu#, Qi NIu, Jianhua Liu, Patrick C. Fraering and Fang Wu*. The FDA-approved natural product dihydroergocristine reduces the production of Alzheimer's disease amylod-abeta peptides. Scientific Reports. 2015 Nov 16;5:16541.

13. 钮琦#, 吴方*. Notch信号通路体外和细胞的药物筛选模型的建立和研究. 药学学报, 2014(6):837-842.

14. Jie Ren, Yuanyuan Zhang, Huizi Jin, Jing Yu, Yueyang Zhou, Fang Wu* and Weidong Zhang*.Novel Inhibitors of Human DOPA Decarboxylase Extracted from Euonymus glabra Roxb.ACS Chem Biol. 2014 Apr 18;9(4):897-903. Cover Story ( IF: 5.4,上海交大SCI B类期刊)

Cited by Sina.com, 文汇报, 中国日报, 京华时报, 中国科学报, Sciencenet.com, 163.com, chinanews.com, bioon.com, ebiotrade.com等

15. Hilal A. Lashuel, Simona Eleuteri, Saviana Di Giovanni, Edward Rockenstein, Mike Mante, Antony Adame, Margarita Trejo, Fang Wu, Patrick C. Fraering, Eliezer Masliah. Novel Mechanism-based Inhibitors of Ab Aggregation and Toxicity. Neurobiology of Aging. 2014:35(3) 720–721.

16. Yueyang Zhou#, Jing Yu#, Xiling Lei, Jianying Wu, Qi Niu, Yixuan Zhang, Hong Liu, Philipp Christen, Heinz Gehring and Fang Wu*. High-throughput tandem-microwell assay identifies inhibitors of hydrogen sulfide signaling pathway. Chem Commun. 2013 Dec 28;49(100):11782-4. (IF: 6.7,上海交大SCI A类期刊)

17. Fang Wu, Philipp Christen, Heinz Gehring. A novel approach to inhibit intracellular vitamin B6-dependent enzymes: proof of principle with human and plasmodium ornithine decarboxylase and human histidine decarboxylase. FASEB J. 2011 Jul;25(7):2109-22.

18. Fang Wu, Claude Schweizer, Nikita Rudinskiy, David M. Taylor, Aleksey Kazantsev, Ruth Luthi-Carter and Patrick C. Fraering. Novel g-secretase inhibitors uncover a common nucleotide-binding site in JAK3, SIRT2 and PS1. FASEB J. 2010 Jul;24(7):2464-74.

19. Fang Wu and Heinz Gehring.Structural requirements for novel coenzyme-substrate derivatives to inhibit intracellular human ornithine decarboxylase and cell proliferation. FASEB J. 2009 Feb;23(2):565-74.

20. Ingrid B.Müller#, Fang Wu#, Bärbel Bergmann, Julia Knöckel, Rolf D. Walter, Heinz Gehring, Carsten Wrenger. Poisoning pyridoxal 5- phosphate (PLP)-dependent enzymes: A new strategy to target the malaria parasite Plasmodium falciparum. PloS ONE. 2009;4(2):e4406. Highlighted by peers in Faculty1000 Biology Pharmacology & Drug Discovery section.  Hanjo Hellmann: Faculty of 1000 Biology, 16 Feb 2009 http://www.f1000biology.com/ article/id/ 1148087 /evaluation

21. Fang Wu, Jing Yu and Heinz Gehring. Inhibitory and structural studies of novel coenzyme-substrate analogs of human histidine decarboxylase. FASEB J. 2008 Mar;22(3):890-7.

22. Fang Wu, Doris Grossenbacher and Heinz Gehring. Transition state based-inhibitor of human ornithine decarboxylase inhibiting growth of tumor cells. Molecular Cancer Therapeutics. 2007 Jun;6(6):1831-9.

 

 

Copyright: 2013 Young Scientist Laboratory of Shanghai Jiaotong University       Technical Support: Shanghai Yi-chao Information Technology Co., Ltd.